Zebrafish offer a nonclinical model for the high-throughput screening of drug compounds, including toxicity assessment, with resolution at the cellular level in living vertebrate organisms. These small, freshwater, tropical fish share genetic and biochemical...
Side effect overload on drug labels has less to do with true toxicity and drug safety than with manufacturer liability. Examination of more than 5600 drug labels yielded over half a million side effects. An average drug label and the more commonly prescribed drugs...
By utilizing the basic principles of hemodynamics and hydraulics, research suggests that fluid retention is detrimental for the cardiovascular system because it increases the likelihood of turbulent blood flow, regardless of whether or not blood pressure is raised. ...
FDA approval does not mean that a drug works well; it means only that the Agency deemed its benefits to outweigh its harms. Comparative efficacy data, other than to placebo, may be missing from the label. In 2006, the FDA revised the drug label design, adding a...
Fundamentals Of Genetic Toxicology In The Pharmaceutical Industry Sept 2010 View more presentations from TigerTox. Historical Overview During the past 30 years, genetic toxicology testing has evolved technologically to play an important safety assessment role in the...
