The objective of a recent survey by Cambridge Health Associates was to identify trends in safety biomarkers and their utilization in drug development. Regardless of company size, recurrent themes for assessing drug safety in early preclinical development were noted....
The increased requirement for combined chronic toxicity and fertility assessment of biologics has led to greater use of sexually mature non-human primates. Older animals have different needs compared to the younger, adolescent animals with which we are used to...
